Model of structural equations on the perception of aspects of school life and substance consumption as predictors of problem behavior in adolescents.

Introduction: Problematic behavior and drug use are behaviors of social concern, especially in adolescence. There are school factors that can contribute to their development or prevent them. The objective was to establish explanatory models of the relationship between various school variables with the consumption of alcohol, tobacco and cannabis; determining its direct and/or indirect relationship with problematic behaviors. Materials and methods: The study was cross-sectional with a sample of 346 students (Main Age=14.81; 54% women) from secondary education. Structural Equation Model (SEM) were carried to analyze the relationship between the dimensions of the Scale of perception of aspects of school life and alcohol, tobacco and cannabis consume with the presence of Problematic Behavior. Results: Problem behavior was predicted by alcohol, tobacco and cannabis consume, and binge drinking. Different aspects of school life differentially predicted problem behavior and drug use. Sense of challenge was observed as having a reciprocal predictive relationship with problem behavior. Perception of oneself at school predicts both alcohol and tobacco use; while the value given to school predicts binge drinking. Discussion: These findings suggests that, when addressing problem behavior and drug use that affect minors in school and have repercussions on class dynamics and academic outcomes, we should not focus exclusively on these problem areas, but rather take a more integrated approach that includes modifying different school-related aspects that act as risk factors for these types of problems.

Consumo de alcohol durante el COVID-19 en Latinoamérica según edad y situación de empleo / Alcohol consumption during COVID-19 in Latin America according to age and employment situation

Esta investigación evaluó el consumo de alcohol en población adulta Latinoamericana y del Caribe latino durante el confinamiento por COVID-19, atendiendo a la edad y situación laboral. Diseño no probabilístico con muestreo por conveniencia, con una muestra de 4975 participantes. Se analizó edad, situación laboral y consumo de alcohol durante el confinamiento y retrospectivamente antes de la pandemia. Los resultados muestran que independientemente del país, los jóvenes de 18-29 años disminuyeron el consumo durante el confinamiento; mientras que el mayor aumento fue en adultos de 45-54 años. Los trabajadores a tiempo completo consumieron más que las personas desempleadas. Empleados a tiempo completo y a tiempo parcial, disminuyeron su consumo durante el confinamiento. Trabajadores por cuenta propia mostraron un consumo de alcohol significativamente superior al de empleados a tiempo completo y a tiempo parcial, durante el confinamiento. Es importante impulsar políticas de prevención del consumo de alcohol en el ámbito laboral. (AU)

This research evaluated alcohol consumption in the Latin American and Latin Caribbean adult population during COVID-19 confinement, taking into account age and employment status. Non-probabilistic design with convenience sampling, with a sample of 4975 participants. Age, employment status and alcohol consumption were analyzed during confinement and retrospectively before the pandemic. The results show that regardless of the country, young people aged 18-29 decreased consumption during confinement; while the largest increase was in adults aged 45-54 years. Full-time workers consumed more than unemployed people. Full-time and part-time employees decreased their consumption during confinement. Self-employed workers showed significantly higher alcohol consumption than full-time and part-time employees during confinement. It is important to promote policies to prevent alcohol consumption in the workplace. (AU)

Dual alcohol and cannabis use in male and female adolescents: Relationships with family variables.

Family dynamics influence adolescents' use of alcohol and other substances, such as cannabis. The aim of this study was to understand the relationship between family variables and alcohol use, dual use of alcohol and cannabis, and non-use in adolescents according to sex. A cross-sectional study was conducted. The sample comprised 879 adolescents (56.4 % boys; M(SD)age = 14.25 (1.88) years). Multinomial regression analysis showed that for boys, the presence of family conflict increased the likelihood of being an alcohol (OR = 1.19) and dual (OR = 1.23) user rather than a non-user. For girls, communication reduced the probability of being an alcohol user (OR = 0.88), and the presence of consequences for breaking rules reduced the probability of being a dual user rather than a non-user (OR = 0.83) or an alcohol user (OR = 0.84). These findings highlight the importance of family prevention of adolescents' substance use, bearing in mind the participants' sex.

Risk and Protective Factors Associated with Drug Use in Healthcare Professionals: A Systematic Review.

Healthcare professionals are exposed to stressful situations that may favor substance use vulnerability. This systematic review aims to synthesize the risk and protective factors associated with use, abuse, and dependence of alcohol, tobacco, psychoactive drugs, and cannabis in healthcare professionals. Following PRISMA recommendations, a systematic search was performed in PsycINFO, Web of Science, PubMed/MEDLINE, Embase, Scopus, and Cochrane Library. The search yielded 1523 studies, of which 19 were selected. The identified risk factors were demographic factors (i.e. male gender, and single/divorced marital status), psychopathological factors, social factors, positive attitudes toward drugs, unhealthy lifestyle habits, the COVID-19 pandemic, and the coexistence of the use of several substances. The protective factors were demographic factors (i.e. ethnicity and having dependent children), healthy lifestyle habits, and workplace anti-drug policies (i.e. restriction of tobacco use). These findings highlight the need for preventive actions against drug use in healthcare professionals to improve their health and reduce the possible negative impact on their healthcare practice. Knowledge of modifiable risk and protective factors allows their incorporation as components in preventive actions, and non-modifiable factors (e.g. demographic variables) may contribute to the detection of groups of greater vulnerability to propose selective prevention actions in this population.

Correction to: Cannabis Use in Young and Adult University Students Before and During the COVID-19 Lockdown, According to Gender and Age.

[This corrects the article DOI: 10.1007/s11469-022-00991-y.].

Prevalence of problematic Internet use and problematic gaming in Spanish adolescents.

Epidemiological studies on problematic Internet use and problematic gaming conducted so far have mainly been carried out with unrepresentative and self-selected convenience samples, resulting in unreliable prevalence rates. This study estimates the prevalence of problematic Internet use and problematic gaming in a large sample of Spanish adolescents (N = 41,507) and identifies risk and protective factors for these risky behaviours. Data were collected online using the Adolescent Problem Internet Use Scale and the Adolescent Gaming Addiction Scale. Using a cut-off approach with measurement instruments inspired by the DSM-5 framework, we found a prevalence of 33% for problematic Internet use and 3.1% for problematic gaming. With a more conservative approach inspired by the ICD-11 framework, prevalence rates decreased to 2.98% for problematic Internet use and 1.8% for problematic gaming. Female gender, higher parents' education, elevated Internet connection time, reporting being online after midnight and using the mobile phone in class predicted problematic Internet use; whereas male gender, "living situation" where families do not have a traditional structure or stable environment, elevated Internet connection time and reporting using the mobile phone in class predicted problematic gaming. A cut-off approach involving scales that recycle substance use criteria (as in the DSM-5) over-pathologize Internet use and gaming behaviours. In contrast, the ICD-11 approach seems to provide more realistic and reliable prevalence rates.

Changes in cannabis use in Spanish consumers during the COVID-19 lockdown according to gender, age, living situation and addiction level. / Cambios en el consumo de cannabis en consumidores españoles durante el confinamiento por la COVID-19 según sexo, edad, situación de convivencia y nivel de adicción.

The objective was to analyze the changes in cannabis use during lockdown considering sex, age, living situation and level of addiction. This descriptive and non-probabilistic study used a convenience sample of 208 participants with ages between 18-57 years (64.3% men; mean age = 31.39 years), that reported consuming cannabis. The frequency of distinct typologies of cannabis use was analyzed and the level of addiction with the Cannabis Abuse Screening Test (CAST). An online survey was used to collect the variables under study. A total of 25% consumers increased their spliff (marijuana mixed with tobacco) consumption, 11.9% increased their joint (marijuana cigarette) consumption and 11.8% increased their hashish spliff consumption. Men had higher levels of cannabis addiction, however, during lockdown they reduced their marijuana spliff consumption while both men and women increased their joint consumption. Marijuana spliff consumption showed a greater increase in the 25-29 age group, in those living with people other than relatives or a partner, alone, or with a partner and was reduced mainly in those living with parents or other relatives. The living alone 18-24 years old group, and the living with parents 35-44 years old group showed higher levels of cannabis addiction (CAST). The rate of dependent consumers who increased their marijuana spliff consumption (49%) doubled compared to consumers with no addiction and moderate addiction. Regarding joints, consumption was 1.5 times higher than for moderate addiction consumers and three times higher than those with no addiction. The risk of cannabis addiction increased in certain groups during lockdown.

El objetivo fue analizar el consumo de cannabis durante el confinamiento según sexo, edad, situación de convivencia y nivel de adicción. Estudio descriptivo no probabilístico con una muestra de conveniencia de 208 participantes con edades entre 18-57 años (64,3% hombres; edad media = 31,39 años) que reportaron consumir cannabis. Se analizó la frecuencia de distintas tipologías de consumo de cannabis y el nivel de adicción con el Cannabis Abuse Screening Test (CAST). La recogida de datos se realizó mediante encuesta online. El 25% de consumidores aumentó su consumo de porros de marihuana mezclada con tabaco; el 11,9% de cigarros de marihuana; y el 11,8% de porros de hachís mezclado con tabaco. Los hombres presentaron mayor nivel de adicción al cannabis. Sin embargo, redujeron su consumo de porros durante el confinamiento. Hombres y mujeres incrementaron su consumo de cigarros de marihuana. El consumo de porros se incrementó mayormente en el grupo de 25-29 años, entre quienes convivían con personas distintas a familiares y pareja, vivían solas, o en pareja; y se redujo entre quienes vivían con progenitores o familiares. Mostraron mayor nivel de adicción al cannabis (CAST) el grupo entre 18-24 años que vive solo y el grupo entre 35-44 años que convive con sus progenitores. Los consumidores con dependencia que incrementan su consumo de porros (49%) fue dos veces superior respecto a los grupos sin adicción y con adicción moderada. El consumo de cigarros de marihuana (20,8%) fue 1,5 veces superior que para adicción moderada y más del triple que para sin adicción. El riesgo de adicción a cannabis aumentó en ciertos grupos durante el confinamiento.

Associations between Sleep, Depression, and Cognitive Performance in Adolescence.

The relevance of cognitive performance during adolescence requires further studies that analyze potential associated factors. This study aimed to analyze inductive reasoning, reading comprehension, and mathematical thinking (problem-solving and number and calculation) in relation to sleep and depression in 244 students aged 12-17 years (47.6% boys and 52.4% girls). Daytime sleepiness, sleep quality, dysthymia, and euthymia (state and trait) were assessed by self-reported questionnaires. Moreover, correlations between these variables and cognitive performance, and differences depending on sociodemographic variables (sex, age, or academic year) were analyzed using non-parametric tests. Robust regression models were also conducted to evaluate the predictive role of significant variables on cognitive performance. The results showed significant bidirectional relationships between sleep- and depression-related variables, and between the latter ones and cognitive performance. Depression-trait was more related to cognitive performance than depression-state, and euthymia more than dysthymia, but neither daytime sleepiness nor sleep quality significantly correlated with it. As for sociodemographic variables, girls reported worse sleep and more depressive symptoms than boys did, and younger students reported better sleep but performed worse than the older ones. Although these findings should be further explored in forthcoming studies adding other promising variables, they highlight the importance of promoting euthymia to improve cognitive performance in adolescents.

Changes in tobacco and e-cigarette consumption in Spanish university students during the COVID-19 lockdown: Identification of vulnerable groups.

INTRODUCTION: The objective of this study was to determine the changes in tobacco consumption in Spanish university students during the lockdown in 2020, and to identify vulnerable groups based on gender, age, and living situation. METHODS: This was a cross-sectional descriptive study. From a sample of 1540 Spanish university students, 19.9% (n=306; 77.6% women; mean age=30.9 years; SD=8.3) reported having consumed tobacco. The frequency and average daily consumption of cigarettes and electronic nicotine delivery systems (ENDS) before the pandemic and during lockdown were analyzed. RESULTS: A total of 97.1% of students consumed only cigarettes, 2.9% only ENDS, and 3.3% were dual consumers. During lockdown, cigarette consumption was significantly reduced (5.3 before; 4.0 during; t(71)=3.6255; p<0.001) in the youngest group (aged 18-24 years). However, women daily users significantly increased their consumption (t(149)= -2.5461; p<0.05) and so did the 35-44 years age group (t(32)= -2.2285; p<0.05). Cigarette consumption significantly increased in those who were living alone (5.6 to 7.2; Z= -2.351; p<0.05) and with a partner (7.2 to 8.0; t(97)= -2.3771; p<0.05), but decreased in those who were living with their parents or other relatives (6.2 to 4.5; t(101)=3.4298; p<0.001). A total of 17.0% ceased consumption during lockdown, mainly women, younger students (aged 18-24 years), and those who lived with their parents. None of the people who used cigarettes daily during the pre-pandemic period stopped smoking during lockdown. CONCLUSIONS: Younger university students and those living with their parents decreased their tobacco use during the lockdown. Potentially vulnerable groups at risk of increasing their consumption were women who consumed tobacco daily before the pandemic and students aged 35-44 years who lived alone or with their partner.

Female Infertility Is Associated with an Altered Expression Profile of Different Members of the Tachykinin Family in Human Granulosa Cells.

Neurokinin B (NKB) and its cognate receptor, NK3R, play a key role in the regulation of reproduction. NKB belongs to the family of tachykinins, which also includes substance P and neurokinin A, both encoded by the by the gene TAC1, and hemokinin-1, encoded by the TAC4 gene. In addition to NK3R, tachykinin effects are mediated by NK1R and NK2R, encoded by the genes TACR1 and TACR2, respectively. The role of these other tachykinins and receptors in the regulation of women infertility is mainly unknown. We have analyzed the expression profile of TAC1, TAC4, TACR1, and TACR2 in mural granulosa and cumulus cells from women presenting different infertility etiologies, including polycystic ovarian syndrome, advanced maternal age, low ovarian response, and endometriosis. We also studied the expression of MME, the gene encoding neprilysin, the most important enzyme involved in tachykinin degradation. Our data show that TAC1, TAC4, TACR1, TACR2, and MME expression is dysregulated in a different manner depending on the etiology of women infertility. The abnormal expression of these tachykinins and their receptors might be involved in the decreased fertility of these patients, offering a new insight regarding the diagnosis and treatment of women infertility.

Profiles and Risk Factors for Teen Dating Violence in Spain.

Teen dating violence (TDV) refers to a wide range of partner-directed harmful behaviors among adolescents. Since it was first documented in the 1980s, there is a growing interest in TDV due to its potentially devastating mid- and long-term consequences. Aiming at the early detection of TDV onset with prevention purposes, research has focused on the detection of typologies of perpetrators and/or victims as well as on identifying risk and protective factors for its occurrence. Research with Spanish adolescents, however, is very limited. To fill this gap, we recruited a total of 2,319 adolescents from different regions in Spain, out of which, 1,079 reported having had a romantic partner during the last year. These filled out measures of TDV (perpetration and victimization), school aggression, hostile and benevolent sexism, empathy, assertiveness, psychological inflexibility (general measures), and psychological inflexibility with prejudice thoughts. A cluster analysis revealed that adolescents could be divided into two clusters as a function of their TDV profile: Cluster 1, including close to 76% of the sample (boys and girls), presented low TDV perpetration and victimization; Cluster 2, including 24% of the sample (boys and girls), presented higher TDV perpetration and victimization. Regression analyses revealed that, as compared to those in Cluster 1, adolescents in Cluster 2 were more likely to be older boys who scored high in benevolent sexism, overt and relational school aggression, and personal distress, and low in behavior regulation skills, perspective taking, and practical personal ability. We discuss the implications of these findings for the design of evidence-based TDV prevention campaigns.

Depression, Suicidal Ideation, and Consumption of Psychotropic Drugs During Lockdown by COVID-19 According to Gender and Age.

The objective was to analyze the relationship between depression and suicidal ideation and psychotropic drugs use during COVID-19 lockdown in adult population considering gender and age. The method used is a descriptive and non-probabilistic study, with a convenience sampling of 3780 participants (70.1% female), aged 18-64 years (M = 37.8). 18.3% participants presented depression and 5.1% exhibited suicidal ideation. The depression rate for female was double (21.4%) than male and 5 times higher (30.2%) for the youngest participants (18-24 years old) compared to oldest (55-64 years old), being this rate triple in suicidal ideation (9%). Depression correlated positively with tranquilizers and sleeping pills' consumption; and suicidal ideation did so with tranquilizers and sedatives. The rate of tranquilizer users was 8 times higher for severe depression compared to those who did not present depression, 5 times higher for sleeping pills, and 6 times higher for sedatives. The rate of tranquilizer users exhibiting suicidal ideation was more than triple than those who did not present suicidal ideation, between 3 and 4 times higher for sleeping pills, and almost 7 times higher for sedatives. The higher the level of depression and suicidal ideation during lockdown, the greater the consumption of psychotropic drugs. The consumption of psychotropic drugs should be monitored in people with depression and suicidal ideation during periods of crisis.

Cannabis Use in Young and Adult University Students Before and During the COVID-19 Lockdown, According to Gender and Age.

The objectives were: (a) to establish cannabis use prevalence in university students; (b) to determine the changes in consumption of cannabis between prior to and during lockdown. Problematic consumption, gender, and age were taken into account to establish risk groups. Of 1,472 participants between 18-54 years (M = 27.51), 8.01% reported using cannabis before and/or during lockdown (56.6% male). The Cannabis Abuse Screening Test (CAST) was used to detect cannabis abuse. The main form of consumption was spliffs (89.9%). The mean of spliffs consumed per day decreased during lockdown, but was only significant in male and in the 18-24 group. This decrease was also significant for all three levels of CAST problematic use. Users with moderate addiction and dependence reduced their average number of spliffs consumed per day during lockdown to a greater extent than those without addiction. These findings establish target groups of prevention interventions in the university.

Problematic Internet Use, Depressive Symptomatology and Suicidal Ideation in University Students During COVID-19 Confinement.

BACKGROUND: The aim was to estimate the rate of PIU in Spanish university students during the lockdown, taking sex and age into account, and to analyze its relationship with depression and suicidal ideation. METHOD: 921 university students (55% women) from 18 to 30 years old (M = 24.8 years; SD = 3) participated. RESULTS: The results showed that 21% of the participants presented PIU, 25.1% moderate depression, 2.1% severe depression, and 6.6% suicidal ideation. The 18 to 21-year-old age group presented the highest rate of PIU (37.8%). A positive correlation was observed between PIU and depression (r = .38; p (241.813) = -8.21; < d = .78) in university students with PIU (M = 9.8; SD = 5.1) than those without it (M = 6.4; SD = 4.1). The rate of severe depression was six times greater (χ2 (3) = 73.25; p < .001) in undergraduates with PIU (6.2%) than those without PIU (0.8%). Moreover, 3.6% of university students with PIU presented suicidal ideation. CONCLUSIONS: These findings establish the association between PIU and depression and suicidal ideation in the university population, providing novel contributions for prevention policies.

[Effects of cannabis use on attention and memory in adolescent population: a systematic review.] / Efectos del consumo de cannabis en la atención y la memoria en población adolescente: una revisión sistemática.

OBJECTIVE: Cannabis is an illegal drug whose use has increased in recent years, especially among adolescents. Despite its popularity, its use and abuse brings with it health consequences, being greater if consumption occurs in the adolescent stage, since the brain is in full development. The objective of this systematic review was to determine the effects of cannabis use on cognitive functions of attention and memory in adolescent population. METHODS: A systematic review of the literature was carried out in the main search portals (Pubmed, Web of Science, SciELO, Cochrane) referring to the last 10 years, following the PRISMA criteria. The systematic search strategy was carried out in the period from March to May 2021, applying the PICO method and the PEDro scale to guarantee the methodological quality of the included studies. RESULTS: Both attention and memory are affected by cannabis use; however, memory functions improve with abstinence, not being so for attention. Memory deficits are an indicator of therapeutic abandonment of addiction treatment. In relation to psychosocial interventions aimed at improving memory, the contingency management, educational interventions and motivational interviewing have not been shown to be effective on the effects of substances. Working memory training offers positive results, although not clinically significant. Finally, memory deficits are an indicator of therapeutic abandonment of pharmacological treatment for cannabis addiction. Therefore, research is needed aimed both at reducing the side effects of drugs on memory processes and at establishing to what extent memory deficits associated with cannabis use can facilitate therapeutic abandonment. CONCLUSIONS: More research is necessary, considering the dual consumption of cannabis-tobacco and the effects that both substances may have jointly and separately on attention and memory processes.

OBJETIVO: El cannabis es una droga ilegal cuyo consumo se ha visto incrementado en los últimos años, especialmente en población adolescente. A pesar de su popularidad, su uso y abuso trae consigo consecuencias para la salud, siendo mayores si el consumo se produce en la etapa adolescente, ya que el cerebro se encuentra en pleno desarrollo. El objetivo de esta revisión sistemática fue determinar los efectos del consumo de cannabis en las funciones cognitivas de atención y memoria en población adolescente. METODOS: Se llevó a cabo una revisión sistemática de la literatura en los principales portales de búsqueda (Pubmed, Web of Science, SciELO, Cochrane) referida a los últimos diez años, siguiendo los criterios PRISMA. La estrategia de búsqueda sistemática se realizó en el periodo de tiempo comprendido entre los meses de marzo a mayo de 2021, aplicándose el método PICO y la escala PEDro para garantizar la calidad metodológica de los estudios incluidos. RESULTADOS: Tanto la atención como la memoria se ven afectadas por el consumo de cannabis; sin embargo, la memoria mejora su funcionamiento con la abstinencia, no ocurriendo lo mismo con la atención. Los déficits de memoria son un indicador de abandono terapéutico del tratamiento para la adicción. En relación con las intervenciones psicosociales orientadas a la mejora de la memoria, tanto el manejo de contingencias como las intervenciones educativas y la entrevista motivacional no se han mostrado efectivas sobre los efectos de las sustancias. El entrenamiento en la memoria de trabajo ofrece resultados positivos, aunque clínicamente no significativos. Finalmente, los déficits de memoria son un indicador de abandono terapéutico del tratamiento farmacológico para la adicción al cannabis, por lo que se precisa investigación orientada tanto a reducir los efectos secundarios de los fármacos sobre los procesos mnésicos como a establecer en qué medida los déficits de memoria asociados al consumo de cannabis pueden facilitar el abandono terapéutico. CONCLUSIONES: Se precisa mayor investigación, considerando el consumo dual de cannabis-tabaco y los efectos que ambas sustancias pueden tener, conjuntamente y por separado, sobre los procesos de atención y memoria.

Efectos del consumo de cannabis en la atención y la memoria en población adolescente: una revisión sistemática / Effects of cannabis use on attention and memory in adolescent population: a systematic review

FUNDAMENTOS: El cannabis es una droga ilegal cuyo consumo se ha visto incrementado en los últimos años, especialmente en población adolescente. A pesar de su popularidad, su uso y abuso trae consigo consecuencias para la salud, siendo mayores si el consumo se produce en la etapa adolescente, ya que el cerebro se encuentra en pleno desarrollo. El objetivo de esta revisión sistemática fue determinar los efectos del consumo de cannabis en las funciones cognitivas de atención y memoria en población adolescente. MÉTODOS: Se llevó a cabo una revisión sistemática de la literatura en los principales portales de búsqueda (Pubmed, Web of Science, SciELO, Cochrane) referida a los últimos diez años, siguiendo los criterios PRISMA. La estrategia de búsqueda sistemática se realizó en el periodo de tiempo comprendido entre los meses de marzo a mayo de 2021, aplicándose el método PICO y la escala PEDro para garantizar la calidad metodológica de los estudios incluidos. RESULTADOS: Tanto la atención como la memoria se ven afectadas por el consumo de cannabis; sin embargo, la memoria mejora su funcionamiento con la abstinencia, no ocurriendo lo mismo con la atención. Los déficits de memoria son un indicador de abandono terapéutico del tratamiento para la adicción. En relación con las intervenciones psicosociales orientadas a la mejora de la memoria, tanto el manejo de contingencias como las intervenciones educativas y la entrevista motivacional no se han mostrado efectivas sobre los efectos de las sustancias. El entrenamiento en la memoria de trabajo ofrece resultados positivos, aunque clínicamente no significativos.(AU)

BACKGROUND: Cannabis is an illegal drug whose use has increased in recent years, especially among adolescents. Despite its popularity, its use and abuse brings with it health consequences, being greater if consumption occurs in the adolescent stage, since the brain is in full development. The objective of this systematic review was to determine the effects of cannabis use on cognitive functions of attention and memory in adolescent population. METHODS: A systematic review of the literature was carried out in the main search portals (Pubmed, Web of Science, SciELO, Cochrane) referring to the last 10 years, following the PRISMA criteria. The systematic search strategy was carried out in the period from March to May 2021, applying the PICO method and the PEDro scale to guarantee the methodological quality of the included studies. RESULTS: Both attention and memory are affected by cannabis use; however, memory functions improve with abstinence, not being so for attention. Memory deficits are an indicator of therapeutic abandonment of addiction treatment. In relation to psychosocial interventions aimed at improving memory, the contingency management, educational interventions and motivational interviewing have not been shown to be effective on the effects of substances. Working memory training offers positive results, although not clinically significant. Finally, memory deficits are an indicator of therapeutic abandonment of pharmacological treatment for cannabis addiction. Therefore, research is needed aimed both at reducing the side effects of drugs on memory processes and at establishing to what extent memory deficits associated with cannabis use can facilitate therapeutic abandonment. CONCLUSIONS: More research is necessary, considering the dual consumption of cannabis-tobacco and the effects that both substances may have jointly and separately on attention and memory processes.(AU)

Problematic Internet Use, Depressive Symptomatology and Suicidal Ideation in University Students During COVID-19 Confinement / Uso Problemático de Internet, Sintomatología Depresiva e Ideación Suicida en Universitarios Durante el Confinamiento por COVID-19

Background: The aim was to estimate the rate of PIU in Spanish university students during the lockdown, taking sex and age into account, and to analyze its relationship with depression and suicidal ideation. Method: 921 university students (55% women) from 18 to 30 years old (M = 24.8 years; SD = 3) participated. Results: The results showed that 21% of the participants presented PIU, 25.1% moderate depression, 2.1% severe depression, and 6.6% suicidal ideation. The 18 to 21-year-old age group presented the highest rate of PIU (37.8%). A positive correlation was observed between PIU and depression (r = .38; p < .001), with a significantly higher mean score on the PHQ-9 (t(241.813) = -8.21; p < .001; d = .78) in university students with PIU (M = 9.8; SD = 5.1) than those without it (M = 6.4; SD = 4.1). The rate of severe depression was six times greater (χ2(3) = 73.25; p < .001) in undergraduates with PIU (6.2%) than those without PIU (0.8%). Moreover, 3.6% of university students with PIU presented suicidal ideation. Conclusions: These findings establish the association between PIU and depression and suicidal ideation in the university population, providing novel contributions for prevention policies.(AU)

Antecedentes: El objetivo fue estimar la tasa de PIU en universitarios españoles durante el confinamiento, considerando sexo y edad, y analizar su relación con depresión e ideación suicida. Método: Participaron 921 estudiantes universitarios (55% mujeres) de 18 a 30 años (M = 24.8 años; SD = 3). Resultados: Los resultados mostraron que el 21% presentaron PIU; 25.1% depresión moderada; 2.1% depresión severa; y 6.6% ideación suicida. El grupo de 18 a 21 años presentó la mayor tasa de PIU (37.8%). Se observó una correlación positiva entre PIU y depresión (r = .38; p < .001), con una puntuación media significativamente mayor en el PHQ-9 (t(241.813) = -8.21; p < .001; d = .78) en universitarios con PIU (M = 9.8; SD = 5.1) frente a los que no la tienen (M = 6.4; SD = 4.1). La tasa de depresión severa fue seis veces mayor (χ2(3) = 73.25; p < .001) en los universitarios con PIU (6.2%) en comparación con los que no tenían PIU (0.8%). El 3.6% de los universitarios con PIU presentó ideación suicida. Conclusiones: Estos hallazgos establecen la asociación entre PIU y depresión e ideación suicida en población universitaria, brindando aportes novedosos para las políticas de prevención.(AU)

Detection of the Synthetic Cannabinoids AB-CHMINACA, ADB-CHMINACA, MDMB-CHMICA, and 5F-MDMB-PINACA in Biological Matrices: A Systematic Review.

New synthetic cannabinoids (SCs) are emerging rapidly and continuously. Biological matrices are key for their precise detection to link toxicity and symptoms to each compound and concentration and ascertain consumption trends. The objective of this study was to determine the best human biological matrices to detect the risk-assessed compounds provided by The European Monitoring Centre for Drugs and Drug Addiction: AB-CHMINACA, ADB-CHMNACA, MDMB-CHMICA, and 5F-MDMB-PINACA. We carried out a systematic review covering 2015 up to the present date, including original articles assessing detection in antemortem human biological matrices with detailed validation information of the technique. In oral fluid and blood, SC parent compounds were found in oral fluid and blood at low concentrations and usually with other substances; thus, the correlation between SCs concentrations and severity of symptoms could rarely be established. When hair is used as the biological matrix, there are difficulties in excluding passive contamination when evaluating chronic consumption. Detection of metabolites in urine is complex because it requires prior identification studies. LC-MS/MS assays were the most widely used approaches for the selective identification of SCs, although the lack of standard references and the need for revalidation with the continuous emergence of new SCs are limiting factors of this technique. A potential solution is high-resolution mass spectrometry screening, which allows for non-targeted detection and retrospective data interrogation.

Visibilización de las estrategias de rebranding y captura corporativa de la salud pública por la industria del cannabis / Visibility of rebranding and corporate capture strategies of public health by the cannabis industry

Cuando las políticas afectan a los determinantes comerciales de la salud, como el alcohol, el tabaco y el cannabis se conoce como captura corporativa de la salud pública. El objetivo del estudio fue visibilizar las estrategias promotoras del cultivo, consumo y regulación del cannabis orientadas hacia una regulación conveniente para la industria, en detrimento de la salud pública. Se siguió un diseño exploratorio cualitativo utilizando un muestro intencional a partir de los diversos canales de información utilizados por la industria del cannabis. Las estrategias de rebranding y captura corporativa halladas se fundamentan en: a) argumentos de desarrollo económico en los que justificar su expansión y una regulación laxa; b) fomento de una imagen positiva del cannabis asociando su consumo a fines de salud y bienestar; c) fomento de una imagen social más aceptable del consumidor, del autocultivador e, incluso, del vendedor; d) la captación y fidelización de consumidores a través de productos derivados del cine, la televisión o los videojuegos, y de manera especial a través de influencers; e) los regalos publicitarios y de patrocinio de eventos dirigidos al “tarjet” de los potenciales consumidores; f) la difusión de fake news que sugieren que el cannabis cura enfermedades; y, g) procesos distorsionadores que afectan a la investigación sobre el cannabis, cuando la financiación proviene de la industria del cannabis. Estos hallazgos ponen de manifiesto las acciones de captura corporativa de la industria del cannabis, orientadas a bloquear o retrasar lasmedidas de salud pública que son contrarias a sus intereses económicos (AU)

When policies affect commercial determinants of health, such as alcohol, tobacco and cannabis, it is known as corporate capture of public health. The aim of the study was to make visible the strategies promoting cannabis cultivation, consumption and regulation oriented towards industry-friendly regulation, to the detriment of public health. An exploratory qualitative design was followed using a purposive sample from the various information channels used by the cannabis industry. The rebranding and corporate capture strategies found are based on: (a) economic development arguments to justify its expansion and lax regulation; (b) promotion of a positive image of cannabis by associating its use with health and wellbeing purposes; (c) promotion of a more acceptable social image of the consumer, the self-cultivator and even the seller; (d) consumer recruitment and loyalty through products derived from film, television or video games, and especially through influencers; e) advertising and event sponsorship gifts aimed at the “tarjet” of potential consumers; f) the dissemination of fake news suggesting that cannabis cures diseases; and, g) distorting processes affecting cannabis research, when funding comes from the cannabis industry. These findings highlight the cannabis industry’s corporate capture actions aimed at blocking or delaying public health measures that are contrary to its economic interests. (AU)

Importance of nutritional assessment tools in the critically ill patient: A systematic review.

Background: Among the risks of the critically ill patient, one of the aspects to be taken into account is the high probability of occurrence of malnutrition risk (40-50%). This process leads to increased morbimortality and worsening. The use of assessment tools allows the individualization of care. Objective: To analyze the different nutritional assessment tools used during the admission of critically ill patients. Methods: Systematic review of the scientific literature related to the nutritional assessment of critically ill patients. Between January 2017 and February 2022, articles were rescued from the electronic databases "Pubmed," "Scopus," "CINAHL" and "The Cochrane Library"; which will analyze which instruments are used during nutritional assessment in the ICU, as well as their impact on mortality and comorbidity of patients. Results: The systematic review was made up of 14 scientific articles that met the selection criteria, obtained from seven different countries. The instruments described were: mNUTRIC, NRS 2002, NUTRIC, SGA, MUST and the ASPEN and ASPEN criteria. All the included studies demonstrated beneficial effects after nutritional risk assessment. mNUTRIC was the most widely used assessment instrument, with the best predictive validity for mortality and adverse outcomes. Conclusion: The use of nutritional assessment tools makes it possible to know the real situation of patients, and by objectifying situations, to allow different interventions to improve the nutritional level of patients. The best effectiveness has been achieved using tools such as mNUTRIC, NRS 2002 and SGA.